Java - Error Ireport y Netbeans

/*

 * To change this template, choose Tools | Templates

 * and open the template in the editor.

 */

package generador_reporte;

import com.lowagie.text.pdf.codec.Base64.InputStream;

import com.sun.xml.rpc.processor.modeler.j2ee.xml.string;

import java.io.IOException;

import java.sql.Connection;

import java.sql.DriverManager;

import java.sql.SQLException;

import java.util.HashMap;

import java.util.Map;

import javax.servlet.ServletConfig;

import javax.servlet.ServletException;

import javax.servlet.ServletOutputStream;

import javax.servlet.http.HttpServlet;

import javax.servlet.http.HttpServletRequest;

import javax.servlet.http.HttpServletResponse;

import net.sf.jasperreports.engine.JasperRunManager;

/**

 *

 * @author investigacion

 */

public class prueba extends HttpServlet {

    @Override

public void init() throws ServletException {

    }

//Process the HTTP Get request

    @Override

    public void doGet(HttpServletRequest request, HttpServletResponse response) throws ServletException, IOException {

        nombre(request, response);

    }

//Process the HTTP Post request

    @Override

    public void doPost(HttpServletRequest request, HttpServletResponse response) throws ServletException, IOException {

        doGet(request, response);

    }

    public void nombre(HttpServletRequest request, HttpServletResponse response) throws IOException {

//         String conn = null;

        try {

            java.io.InputStream in = this.getClass().getResourceAsStream("C:/Users/investigacion/Documents/NetBeansProjects/prueba_reporte/web/reportes/datos_paciente.jasper");

            Map parameters = new HashMap();

            byte[] bytes = JasperRunManager.runReportToPdf(in, null, getConnection());

            response.setContentType("application/pdf");

            response.setContentLength(bytes.length);

            ServletOutputStream ouputStream = response.getOutputStream();

//la siguiente linea, te obliga a descargar y le da el nombre//

            response.addHeader("content-disposition", "attachment; filename=DatosPaciente.pdf");

            ouputStream.write(bytes, 0, bytes.length);

            ouputStream.flush();

            ouputStream.close();

        } catch (Exception e) {

// out.println(e.getMessage());

        }

    }

    public static Connection getConnection() throws ClassNotFoundException, SQLException {

        String driver = "com.ibm.db2.jcc.DB2Driver";

        String connectString = "jdbc:db2://10.0.3.60:50000/TICS2";

        String user = "administrator";

        String password = "bolivar112710";

        Class.forName(driver);

        Connection conn = DriverManager.getConnection(connectString, user, password);

//Retornamos la conexión establecida.

        return conn;

    }

}